Endocrine Abstracts

Objectives: To evaluate the psychosocial aspects and the common dietary habits in a group of patients in follow-up in specific consultation of bariatric surgery prior to the intervention.Methods: Cross-sectional study of patients in follow-up in the specific morbid obesity consultation of the University Hospital Puerta del Mar (Cádiz) not intervened.Results: 110 patients were analyzed, of which 68.2% are women, with an average...

Objectives: To evaluate the psychosocial aspects and the common dietary habits in a group of patients undergoing bariatric surgery.Methods: Cross-sectional study of patients in follow-up in the specific consultation of morbid obesity of the University Hospital Puerta del Mar (Cádiz) intervened, at 6–12 months of follow-up.Results: 88 patients were analyzed, of which 70.5% (N=62) are women, with an average age of ...

Aims: To evaluate the clinical features and long-term therapeutic outcome of giant prolactinoma (gPRLoma) in men and to compare them with those of a group of male patients with non-gPRL macroprolactinomas (non-gPRLomas).Patients and methods: A retrospective and multicenter study of gPRLomas in men diagnosed in a 20-year period was performed. Clinical data and treatment outcome were registered. The diagnosis of gPRLoma was established when the maximal tum...

Introduction: Hypothyroidism in pregnancy is a topic widely studied in recent years, especially in those women with positive autoimmunity. However, usually the only determination of antibodies that is made is the thyroid antiperoxidase antibodies (anti-TPO). In this study we wanted to know what incidence of anti-thyroglobulin antibodies (anti-Tg) our pregnant women present and what repercussion they can have on thyroid function.Materials and methods: Ant...

Objectives: The aim of this study was to analyze the prevalence of some polymorphisms of the CTR-AluI, VDR-FokI, Col1A1y ER-α genes, (involved in bone metabolism), in our population. And evaluate the association of these polymorphisms with bone mineral density and fracture.Design, Patients, and Setting: We performed an observational prospective study in pre- and postmenopausal ambulatory women (n=72 and n=152, respectively).<p ...

This is a 38-year-old male, a regular user of a gym with the sole purpose of improving his physical performance and muscular strength and habitual consumer of hyperproteic dietary supplements. Among his PAs he denies toxic habits, and highlights the removal of the right testicle in childhood. Consultation for decreased desire and sexual potency, together with pain and turgor in the left breast; hair loss at the frontal level, in analytic carried out by the Primary Care Physici...

Background: Obesity is a growing global health problem and currently bariatric surgery (BS) is the best solution in terms of sustained total weight loss (TWL). However, a significant number of patients present weight regain (WR) in time. There is a lack of biomarkers predicting the response to BS and WR during the follow-up. Plasma SHBG levels, which are low in obesity, increase one month after BS but there is no data of plasma SHBG levels at long term. We performed the presen...

Objective: Non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) it’s a histological entity that describes a low-aggressive neoplasm previously classified as encapsulated follicular variant of papillary thyroid carcinoma and well differentiated tumour of uncertain malignant potential. The preoperative diagnosis it’s difficult, and if we suspect it hemithyroidectomy or lobectomy it’s the therapeutic management of choice. Therefore,...

Introduction: Epigenetic is acquiring great importance in complex diseases, providing mechanisms whereby environmental factors can influence complex diseases such as obesity and type 2 diabetes. Experimental animal and human studies have revealed the association between SCD1 and obesity and insulin resistance. The aim of this study was to evaluate whether metabolic changes after intervention are associated with DNA methylation pattern and if these changes are related to weigh ...

Introduction: The stearoyl-CoA desaturase 1 (SCD1) is an enzyme involved in the metabolism of fatty acids, and seems to be involved in the regulation of atherosclerosis development. In this study we want to check the expression of SCD1 in visceral and subcutaneous adipose tissue and its relationship with the metabolic syndrome.Methods: We measured SCD1 mRNA and protein expression in visceral and subcutaneous adipose tissue from 25 morbidly obese patients...